Case Study:
A 65 year old male presents with a painful left finger unable to bend and is significantly swollen.  He has a history of osteoarthritis.

1. OA is a disease of articular cartilage and subchondial bone in diarthrodial joints.  Explain this.
2. What is the role osteophytes in OA?
3. How do NASAIDS affect  OA?
4. How does weight loss affect OA?

Requirements:
Citations: At least one high-level scholarly reference in APA from within the last 5 years